P03002010 CHEVROLET Suburban

P0300 on 2010 CHEVROLET Suburban

Random/Multiple Cylinder Misfire Detected

💬
6
Discussions
33%
Success Rate
👥
12
Owner Reports
Live Data

Last reported case: 2 months ago

Based on 6 owner reports, 6 from forums)

What is P0300?

P0300 indicates your engine is misfiring across multiple cylinders, which is a critical powertrain issue that can cause severe engine damage if ignored. This code triggers when the engine control module detects irregular combustion in several cylinders, often leading to rough running, power loss, and potential catalytic converter damage. Based on real data, this is most commonly reported in Honda Accord, Chevrolet Spark, and Ford Mustang models.

Common Causes:

  • Faulty spark plugs or ignition coils (mentioned in multiple Spark and Accord cases)
  • Head gasket failure (specifically mentioned in Honda Accord discussions)
  • Fuel system issues like failing fuel pumps (referenced in Accord owner quotes)
  • Worn engine components in high-mileage vehicles (seen in 130k+ mile Spark and 324k mile Accord examples)

Symptoms:

  • Engine runs rough or shakes noticeably (implied in misfire descriptions)
  • Loss of power or acceleration (mentioned in Mustang and Accord cases)
  • Check engine light illumination with possible limp mode activation (specifically described in 2020 Accord case)
  • Poor fuel economy and potential stalling (inferred from misfire behavior)

View generic P0300 info →

🚗P0300 on 2010 CHEVROLET Suburban

This page focuses specifically on P0300 issues reported by 2010 CHEVROLET Suburban owners. The experiences and fixes below are from real owners of this exact vehicle.

Symptoms Reported by 2010 CHEVROLET Suburban Owners:

white smokemisfiresvacuum leakmisfire

Parts Often Involved:

bosch injectorsspark plugsinjector dataexhaustinjectoro2 sensorfuel linescrank sensor o ringrestriction exhaustfuel pump

What Owners Say

Real experiences from 2010 CHEVROLET Suburban owners

12 reports
Pro Tipvia forum_reply
FSM tells you exactly what you should see. Also, exhaust system near the O2 sensors on these beasts can not have leaks or things will not work perfectly.
toolmakersonJan 2026
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Experiencevia forum_reply
At idle if i pinch the return line i can make the pressure easily hit 65-70 psi. Fuel pressure has NOT been checked again after the intake, injector, fpr replacement.
98_FamilyJan 2026
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Experiencevia forum_reply
Fuel pressure was one thing that popped out at me that you did not mention. Pressure can also be ok at lower power levels, but when engine is under load and using lots of fuel, fuel system can be a little too weak to supply enough fuel AND keep the pressure high enough.
toolmakersonJan 2026
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Experiencevia forum_reply
Engine idling fuel pressure was 47-48 psi and will jump to 57 or so if you blip the throttle. At idle if i pinch the return line i can make the pressure easily hit 65-70 psi.
98_FamilyJan 2026
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Fixed Itvia forum_post
And I also in all this craziness fixed the knock sensor code and its never come back. But that was there before 0411 swap.
98_FamilyJan 2026|Problem Fixed
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Experiencevia forum_reply
I was glancing at P0172/5 you might want to look at those sections as well. I couldn't find the exact O2 sensor oscillation spec, it's like 900 I think on the top end, I'm not sure about the bottom end, maybe 400.
toolmakersonJan 2026
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Experiencevia forum_post
Gunna be a long post but hoping to share my experience and maybe get some help. 1999 K2500 LS with 7.4l. Had a couple issues I knew of when I bought like a cobbled together exhaust and a check engine light.
98_FamilyJan 2026
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Experiencevia forum_reply
I couldn't find the exact O2 sensor oscillation spec, it's like 900 I think on the top end, I'm not sure about the bottom end, maybe 400. I believe these are mV.
toolmakersonJan 2026
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Experiencevia forum_reply
Both need to be correct before you can move on to tuning a VE table. I am completely ignorant on what the L29 guys are shoving into their engines injector wise.
L31MaxExpressJan 2026
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Experiencevia forum_reply
Do you have a Bosch part number and do those injectors come with GM characterization data? On my buddys truck with the 454 we talked ahead of time and he went with cleaned and flow matches LS1 injectors that have good GM data.
L31MaxExpressJan 2026
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These are real experiences shared by 2010 CHEVROLET Suburban owners on automotive forums and communities. Results may vary based on vehicle condition and repair quality.

About This Data

This page aggregates 6 discussions about P0300 from 2010 CHEVROLET Suburban owners across automotive communities.

Success rate (33%) is calculated from posts where owners confirmed whether their fix resolved the issue.

Last updated: 1/3/2026